Good afternoon ladies and gentlemen. Thanks for coming to this late in the week and this late on the Friday to a talk that I'm very certain will make it worth your effort.

I'm very pleased and honored and proud to present to you today Professor Ken Barich from the University of Michigan in Arbor.

He is the James Oltz Distinguished University Professor of Psychology in Neuroscience.

Sounds fancy, is fancy because James Oltz is one of the founding fathers of modern neuroscience and he also worked for an amount of time at the University of Michigan, hence the heritage of that distinguished professorship.

Ken Barich is I would say the world leading expert on the neuroscience of motivation and that is being manifest in a lot of things that he did and a lot of the accolades that he won.

One is the James Oltz Distinguished Professorship that he has at the University of Michigan.

He was also recently in 2019 I think together with Terry Robinson awarded the Gravamaia Award in Psychology for influential ideas in psychology

and this of course pertains to his contribution of the terms wanting and liking to our arsenal of concepts in motivation science.

He was awarded in 2016 the Distinguished Scientific Contributions Lifetime Award by the American Psychological Association.

He is a fellow of the American Association for the Advancement of Science.

He was a Guggenheim Fellow and this goes on and on.

I just cite you the most recent accolades.

He has been listed among the 50 most influential living psychologists in 2018.

If you look at as our university president is fond of doing, if you look at his Google age score you will see that it has passed the 100 thresholds.

This is kind of the stratosphere of where you can get if you are not only brilliant but also productive and not only that but if whatever you write also has an impact on other people.

So this is not just Kent citing himself but never gets you there, this is a lot of people in motivation science and neuroscience and clinical science

working with the concepts and with the insights that Kent Berridge and his collaborators have produced in their labs.

He is the author of about 300 publications, book chapters, articles.

He was a visiting scholar at the University of Liverpool, the University of Cambridge and University College London.

He is currently a visiting professor at the University of Sussex.

When I learned that earlier this year I thought wow this is a great moment to get Kent Berridge to come to visit Erlangen because he is close by, he is in Europe.

For those of you who have doubts Great Britain geographically at least is still part of Europe.

So that made it easy to invite him here and I am very grateful and honored for you to be here today Kent and we look forward to your talk.

Please welcome with me Kent Berridge.

Thank you Oliver, that was much kinder than I deserve and I am grateful to all of you for coming on a Friday.

I understand that there aren't so many lectures on Fridays.

Today I have always wanted to come and visit Erlangen, I have heard so much about it for so many years

and so it is a pleasure to come and see the beautiful town, the beautiful region and the distinguished university here.

Today I would like to talk about desire, delight and dread.

I am going to focus mostly on desire and delight, that is wanting and liking and how they go together in the brain and how they come apart.

But also I would like to talk a little bit about a counterintuitive relationship between desire, wanting on the one hand

and dread or fear and anxiety on the other hand, counterintuitive because they are opposites but the brain says there is something in common.

So that is the major theme, wanting and liking.

In green here we have sort of the large wanting system in the brain that mediates wanting for pleasant things

and I will talk a little bit about the smaller liking system, the little red dots that are small, fragile, embedded in the wanting system.

So liking and wanting.

And the goal of my talk is to give you a sense of where did this idea come from, wanting and liking separating in the brain.

Then to give you a sense of what is new, what is happening that is kind of exciting in the lab now, cutting edge things.

And finally to give you a sense of clinical applications of these ideas to human clinical disorders,

addictions, schizophrenia, depression to see what applications it has.

So that is the three things, the history of the idea, new developments and clinical applications.

And maybe to start it is worthwhile asking well how general is what I will say about wanting and liking.

How general is it to all the things we want and like or is it just a few of those things?

My view of that has changed over the years.

I am going to be talking a lot about the dopamine reward system which even 30 years ago people agreed,

was shared by all different sensory rewards, food, sex, drugs, electrical brain stimulation rewards

that people and animals would work for, all kinds of sensory rewards.

If you had asked me 20 years ago, I would have said that this green brain system is mostly for sensory rewards

and not so much for human cognitive cultural rewards.

But I was wrong I think 20 years ago because the last 20 years of neuroimaging data in humans