Okay, so welcome everyone to this year online seminar. We have Professor Martin Berger from
the chair of Applied Mathematics 1 here at FRO and he will be speaking about adaptive
computation of sparse solutions. Please, Professor Berger, you have the floor.
Thanks a lot. Yeah, so I was, ah, it does not work to go on. Yeah, okay. So, yeah, I
was asked to talk about this topic today. It's a joint work mainly with Alexandra Kulluri,
who was a postdoc when I was in Munster and has now two half positions in Finland, I guess,
for the summer and in Basford winter. And also with Pia Heinz, who was a PhD student
a few years ago, then went to Bosch and is now in Hannover at the Technical University
or University of Applied Sciences. And in the second part, I will mention about a related
work recently with Pratim Pataturi and Uncle Berner at the DLR in Berlin and also Benjamin
Mormsten, who is actually, I think today has his last, his last day at FRO, was involved
there. So what we are interested in is, yeah, mainly motivated by imaging. There are some
other problems where you have similar issues. So we look for the resolution of some spike
or I would say delta peak structure. And this can be either in space or in time or in frequency
or maybe also in some, in some continuum or in some basis in an infinite dimensional Hilbert
space. So like in a wavelet basis or something similar. But mainly I will talk about really
a continuum. So I could think about either R1 as time or frequency or R2 or R3 for imaging.
And some applications that, yeah, we are particularly working on is one, the localization of structure
in super resolution microscopy. So in super resolution microscopy, you now get to resolutions
really where you see single proteins. So which are really like single points in the image.
Another interesting thing is peak detection in spectroscopy, in particular when it gets
from chemistry or physics towards biology, where you have very complicated spectra and
it's not so easy to pick some peaks by hand. And another maybe interesting problem is the
localization of brain activity with electric or magnetic recordings on the brain surface.
So it's like the typical brain activities at a certain time, but it's like a combination
of several, it's not really delta peaks, it's really a dipole. So it's really like a divergence
of the delta peak times a vector, but you can still formulate the source localization
is a estimation of some delta peaks. Okay. And as I said, like also in spectroscopy,
which is common, if you have only few or very few of them, like one, two, three that are
very pronounced, you can do some simple methods. So in spectroscopy people may pick peaks by
hand from the data or in eGMEG, this is called dipole fitting. So in very simple standard
experiments where you only have one or two sources in the brain, you could just make
an ansatz of a sum of two or linear combination of two delta peaks and then find the locations
and the coefficients explicitly. Okay. But if you get to more relevant things, then you
get into very complicated structures. So for example, you would have in microscopy or in
spectroscopy, you have the convolution of several or linear combination of several delta
peaks with some kernel. And then it's not so easy to find the peaks. And in brain activity,
if you think about real relevant diseases like epilepsy, you have a lot of brain activity
at the same time, and then you cannot just pick a few of them. And just as a side comment,
there is a paper by Bach and CoArthur who also relate this to the training of neural
networks. So if you want to train compact sparse neural networks with as few entries
as possible, kind of you have similar problems here. Okay. So let me start with the simplest
model and also the most frequent one in applications is just the convolution. So we have a forward
model where we have measured a function f, which is the convolution of some kernel G.
You can think of some Gaussian to make it easy with a density in this case, typically
even a non-negative density, but for my analysis that does not play a role. So in some cases,
you can also have signs in applications. And if you think for, look for spikes or peaks,
then as I said, you look for a mu that is a linear combination of delta peaks at certain
unknown locations psi L. Okay. And the total number, capital L of these peaks is also an
unknown. So you see it's a complicated problem to estimate. Okay. What you can do is an appropriate
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Aufnahmedatum
2021-03-31
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